AbstractPeriodontal tissue disease is one of the most widespread human diseases. The development of periodontal tissue diseases (generalized periodontitis) depends on many local and systemic risk factors. An important place is the emergence of diseases of periodontal tissues against the background of a violation of the normal functioning of antioxidant defense systems, which leads to the development of oxidative stress and dysfunction of cells and tissues of the oral cavity. The aim of the study was to determine some indicators of oxidative stress in 2-year students of a medical university with an initial-I degree of generalized periodontitis. To assess the level of oxidative stress, indicators such as malonic aldehyde (MDA), SOD (superoxide dismutase) and glutathione peroxidase were used. The results of the study showed that oxidative stress plays an important role in the pathogenesis of periodontal tissue diseases.
AlMoharib HS, AlMubarak A, AlRowis R, Geevarghese A, Preethanath RS, Anil SJ. Oral fluid based biomarkers in periodontal disease: part 1. Saliva. Journal of International Oral Health. 2014;6(4):95-103. [PMid:25214743 PMCid:PMC4148585]
Almerich-Silla JM, Montiel-Company JM, Pastor S, Serrano F, Puig-Silla M, Dasí F. Oxidative Stress Parameters in Saliva and Its Association with Periodontal Diseases and Types of Bacteria. J Disease Markers [Internet]. 2015. Available from: http://dx.doi.org/10.1155/2015/653537 DOI: 10.1155 / 2015/653537 DOI: https://doi.org/10.1155/2015/653537
Zadik Y, Bechor R, Shockat Z, Galor S. Ethnic origin and alveolar bone loss in Israeli adults in Hebrew. Refuat Hpeh vehashinayim. 2008;25(2):19-22.
Buatongsri V, Songpaison Y, Hong Prasong N, Phantumvanti P, Clark N. Distribution of pf severe periodontitis in urban (Bankok) and rural (payao province) high risk to stress group of this population. Cu Dent J. 2002;25:1-4.
Konovalova OV. Influence of psychoemotional stress on the state of periodontal tissues (review of literature). Bulletin of Biology and Medicine. 2016;1(133):36-40.
Castillo DM, Sanchez-Beltran MC, Castellanos JE, Sanz I, Mayorda-Fayad I, Sanz M et al. Detection of specific periodontal microorganisms from bacteriemia samples after periodontal therapy using molecular-based diagnostics. J Clin Periodontol. 2011;38:418-427. DOI: https://doi.org/10.1111/j.1600-051X.2011.01717.x [PMid:21392048]
Cronin AJ, Claffey N, Stassen LF. Who is at risk? Periodontal disease risk analysis made available to the general dentist. Br Dent J. 2008;205(3):131-137. DOI: https://doi.org/10.1038/sj.bdj.2008.653 [PMid:18690185]
Reners M, Breex M. Stress and Periodontal Disease. Int J Dent Hyg. 2007;5(4):199-204. DOI: https://doi.org/10.1111/j.1601-5037.2007.00267.x [PMid:17927631]
Rivera C, Monsalve F, Suazo I, Becerra J. Stress increases periodontal inflammation. Exp Theor Med [Internet]. Nov. 2012;4(5):883-888. Available from: https: //www.ncbi.nlm.nih.gov/pmc/articles/PMC3493748/ DOI: 10.3892 / enm.2012.675.
Neporoda KS, Berehova TV, Sukhomilin AA, Gordienko LP, Mykytenko AO. Development of oxidative stress of the organs of the oral cavity under different conditions (review of literature). Southeastern Medical Journal. 2017;18(18):81-84.
Pinda MY, Yakymets MM, Karkinska GB. Indicators of homeostasis of the cavity of the mouth in 6-year-old children with high intensity of caries of teeth. Bulletin of Biology and Medicine. 2014;4(116):354-356.
Litvinets LJ. Oxidative stress and antioxidant protection in children with varying degrees of bronchial asthma control. Child health. 2013;8(51):71-74.
Armstrong D. Oxidative Stress Biomarkers and Antioxidant Protocols. Totowa, New Jersey: Humana Press Inc.; 2002.186p. DOI: https://doi.org/10.1385/1592591736
Vladyka AS, Levytsky ER, Poddubnaya LP. Medium molecules and the problem of endogenous intoxication in critical states of different etiologies. Anesthesiology and Reanimatology. 1987;2:17-19.
Panjamurthy K, Manoharan S, Ramachandran CR. Lipid peroxidation and antioxidant status in patients with periodontitis. Cell Mol Biol Lett. 2005;10:255-264. [PMid:16010291]
Canakci CF, Cicek Y, Yildirim A, Sezer U, Canakci V. Increased levels of 8-hydroxydeoxyguanosine and malondialdehyde and its relationship with antioxidant enzymes in the saliva of periodontitis patients. Eur J Dent. [Internet]. April 3, 2009(3):100-6. Available from: https://www.ncbi.nlm.nih.gov/pubmed/19421389. [PMid:19421389 PMCid:PMC2676068]
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