Thyroid Volume and Doppler Indices of the Inferior Thyroid Artery in Clinically Euthyroid Adults in Kashmir
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Keywords

peak systolic velocity
pulsatility index
resistivity index
inferior thyroid artery
thyroid function

Abstract

The objective of the research was to evaluate thyroid volume and spectral indices (the resistivity index, the pulsatility index and the peak systolic velocity) in normal euthyroid adults in Kashmir.         Materials and methods. There was carried out a prospective observational study at a tertiary care hospital; 182 normal euthyroid adults (102 males and 80 females) were included in the study. Thyroid gland volume was calculated from grey-scale ultrasound images followed by spectral Doppler evaluation of the bilateral inferior thyroid arteries; the resistivity index, the pulsatility index and the peak systolic velocity were calculated for the bilateral inferior thyroid arteries with calculation of the mean values.         Results. The mean thyroid volume was 7.8±1.9 ml with no significant difference in males and females. The mean peak systolic velocity obtained was 15.65±6.5 cm/s. The mean pulsatility index and resistivity index were 0.95±0.29 and 0.58±0.13, respectively. There was no significant difference in the values obtained among both genders, and no significant difference was seen in values of the right and left inferior thyroid arteries.         Conclusions. The study showed no significant difference in the indices of thyroid volume and the inferior thyroid arteries measured by Doppler ultrasonography in euthyroid adult males and females. As thyroid vascularity is altered in many thyroid pathologies, the study will serve as the baseline for the evaluation of thyroid volume and Doppler parameters in patients with altered thyroid function. 
https://doi.org/10.21802/gmj.2018.3.1
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References

Jebreel AE, England J, Bedford K, Murphy J, Karsai L, Atkin S. Vascular endothelial growth factor (VEGF), VEGF receptors expression and microvascular density in benign and malignant thyroid diseases. Int J Exp Pathol. 2007;88:271‑277. DOI: https://doi.org/10.1111/j.1365-2613.2007.00533.x

Wang JF, Milosveski V, Schramek C, Fong GH, Becks GP, Hill DJ. Presence and possible role of vascular endothelial growth factor in thyroid cell growth and function. J Endocrinol. 1998;157:5‑12. DOI: https://doi.org/10.1677/joe.0.1570005 [PMid:9614352]

Ruchała M, Szczepanek E. Thyroid ultrasound - a piece of cake? Endokrynol Pol 2010;61:330‑344. [PMid:20602310]

Bogazzi F, Bartalena L, Brogioni S, Burelli A, Manetti L, Tanda ML et al. Thyroid vascularity and blood flow are not dependent on serum thyroid hormone levels: Studies in vivo by color flow sonography. Eur J Endocrinol. 1999;140:452‑456. DOI: https://doi.org/10.1530/eje.0.1400452 [PMid:10229913]

Zhao X, Chen L, Li L, Wang Y, Wang Y, Zhou L et al. Peak systolic velocity of superior thyroid artery for the differential diagnosis of thyrotoxicosis. PLoS One. 2012;7:e50051. DOI: https://doi.org/10.1371/journal.pone.0050051

Huang SM, Chow NH, Lee HL, Wu TJ. The value of color flow Doppler ultrasonography of the superior thyroid artery in the surgical management of Graves' disease. Arch Surg. 2003;138:146‑151. DOI: https://doi.org/10.1001/archsurg.138.2.146 [PMid:12578408]

Macedo TA, Chammas MC, Jorge PT, De Souza LP, Farage L, Pegoraro BL et al. Reference values for Doppler ultrasound parameters of the thyroid in a healthy iodine‑non‑deficient population. Br J Radiol. 2007;80:625‑630. DOI: https://doi.org/10.1259/bjr/69016171

Ueda M, Inaba M, Kumeda Y, Nagasaki T, Hiura Y, Tahara H et al. The significance of thyroid blood flow at the inferior thyroid artery as a predictor for early Graves' disease relapse. Clin Endocrinol (Oxf). 2005;63:657‑662. DOI: https://doi.org/10.1111/j.1365-2265.2005.02397.x

Sostre S, Reyes MM. Sonographic diagnosis and grading of Hashimoto's thyroiditis. J Endocrinol Invest. 1991;14(2):115-121. DOI: https://doi.org/10.1007/BF03350281 [PMid:1648115]

Berghout A, Wiersinga WM, Smits NJ, Touber JL. Determinants of thyroid volume as measured by ultrasonography in healthy adults in a non-iodine deficient area. Clin Endocrinol (Oxf). 1987;26(3):273-80. DOI: https://doi.org/10.1111/j.1365-2265.1987.tb00784.x

Uchida T, Takeno K, Goto M, Kanno R, Kubo S, Takahashi S et al. Superior thyroid artery mean peak systolic velocity for the diagnosis of thyrotoxicosis in Japanese patients. Endocr J. 2010;57:439‑443. DOI: https://doi.org/10.1507/endocrj.K09E-263 [PMid:20513982]

Banaka I, Thomas D, Kaltsas G. Value of the left inferior thyroid artery peak systolic velocity in diagnosing autoimmune thyroid disease. J Ultrasound Med. 2013;32(11):1969-1978. DOI: https://doi.org/10.7863/ultra.32.11.1969

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