AbstractThe objective of the research was to estimate the early and remote results of surgical treatment in patients with deep vein thrombosis of the inferior vena cava.Material and methods. The results of treating 790 patients with lower limb deep vein thrombosis and thrombosis of the inferior vena cava were analyzed. Depending on treatment, all the patients were divided into the following groups: Group IA consisted of 380 (68.5%) patients with deep vein thrombosis who underwent open complete or partial thrombectomy with or without surgical prevention of pulmonary thromboembolism; Group IB consisted of 50 (9.0%) patients with deep vein thrombosis who received combined treatment with surgical prevention of pulmonary thromboembolism; Group IC consisted of 125 (22.5%) patients with transfascial thrombosis who underwent thrombectomy of the apical thrombotic masses of deep veins followed by radical venectomy; Group II consisted of 235 (29.7%) patients with deep vein thrombosis who received conservative anticoagulant therapy only.For investigation of patients, there were used the following laboratory methods of examination: duplex ultrasound scanning, X-ray phlebography, computer tomography, echocardioscopy and radionuclide phleboscintigraphy.Results. The results of surgical and combined methods of treating deep vein thrombosis in clinical subgroups were evaluated using a three-point scale - good, satisfactory and unsatisfactory. The cumulative analysis of the results of the postoperative period during 3 years of follow-up showed that good and satisfactory results were observed in 89.3% of patients of Group IA, 81.7% of patients of Group IB, 88.4% of patients of Group IC, and 35.3% of patients of Group II. Three years after treatment, the signs of chronic venous insufficiency were found in 51.6% of patients who underwent conservative treatment, 36.4% of patients who received combined treatment, 10.2% of patients who underwent partial thrombectomy, 2.9% of patients who received surgical treatment of transfascial thrombosis; they were absent in patients who underwent radical thrombectomy.Conclusions. In quantitative evaluation of the early and remote results of treating deep vein thrombosis of the inferior vena cava, a significant improvement in the patients’ condition in all parameters was observed in the main group as compared to the control one.
Boiko VN, Bereznytskyi YaS, Venher IK et al. Venoznyi tromboembolizm: diahnostyka, likuvannia, profilaktyka. Mizhdystsyplinarni klinichni rekomendatsii. Kyiiv; c2013. 63p.
Hudz IM. Diahnostyka ta likuvannia hostroho trombozu hlybokykh ven nyzhnikh kintsivok i tazu. Rekomendatsii Tovarystva sudynnykh khirurhiv Nimechchyny. Sertse i sudynu. 2006;2(14):34-36.
Kobza II, Havryliv BM. Kompleksne likuvannia trombozu hlybokykh ven, uskladnenoho tromboemboliieiu lehenevoii arterii. Klinichna flebolohiia. 2008;1(1):12-14.
Kosynskyi OV, Buzmakov DL, Rzhemovskyi VV. Struktura invalidnosti vnaslidok zakhvoriuvan ven nyzhnikh kintsivok v Ukraiini za 2013 rik. Klin. flebolohiia. 2014;17(1):100-103.
Bodnar V. Lecheniye ostroy venoznoy tromboemboliyi i profilaktika yeye retsidivov: aktsent na peroralnye antikoagulyanty. Medicine Review. Kardiologicheskiy almanakh. 2015;65-78.
Kobza II, Havryliv BM, Orel YuH, Zhuk RA, Orel MH, Kikhtiak AT et al. Likuvannia flebotromboziv systemy nyzhnoii porozhnystoii veny, uskladnenykh flotatsiieiu verkhivky trombu. Nauk. visnyk Uzhhorodskoho universytetu, seriia "Medytsyna". 2012;2(44):52-53.
Prasol VA, Mishenina YeV, Okley DV. Taktika vedeniya patsiyentov pri prodolzhayushchemsya ostrom tromboze glubokikh ven. Klinichna khirurhiia. 2015;3(871):36-38.
Rusyn VI, Levchak YuA, Boldizhar PO. Osoblyvosti khirurhichnykh vtruchan pry flotuiuchykh trombakh u systemi nyzhnoii porozhnystoii veny. Kharkivska khirurhichna shkola. 2006;3(30):38-41.
Nebylitsin YuS, Sushkov SA, Samsonova IV, Krylov YuV. Struktura letalnosti pri tromboemboliyi legochnoy arteriyi v statsionarakh Vitebska za 15 let. Novosti khirurgiyi. 2008;1 (1):62-66
Boiko VN, Boldizhar PI, Venher IK et al. Ukraiinski mizhdystsyplinarni klinichni rekomendatsii po profilaktytsi, diahnostytsi ta likuvanniu venoznykh tromboembolichnykh uskladnen. Klinichna flebolohiia. 2017;10(1):42-104.
Konstantinides SV, Torbicki A, Agnelli G, Danchin N, Fitzmaurice D, Galie N et al. 2014 ESC Guidelines on the diagnosis and management of acute pulmonary embolism. The Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC) Endorsed by the European Respiratory Society (ERS). Eur Heart J. 2014;35(43):3033-3069. DOI: https://doi.org/10.1093/eurheartj/ehu283
Kearon C, Akl EA, Ornelas J, Blaivas A, Jimenez D, Bounameaux H et al. Antithrombotic Therapy for VTE Disease: CHEST Guideline and Expert Panel Report. American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (10th Edition). Chest. 2016;149(2):315-352. DOI: https://doi.org/10.1016/j.chest.2015.11.026
Geier B, Asciutto G, Strohmann B. Long-term results after transfemoral venous thrombectomy for iliofemoral deep venous thrombosis. Abstracts XXIII Annual Meeting European Society for Vascular Surgery (3 - 6 September 2009, Oslo, Norway): 148.
Nicolaides AN, Fareed J, Kakkar AK, Comerota AJ et al. Prevention and treatment of venous thromboembolism. International Consensus Statement. Int Angiol. 2013;32(2):111-260. [PMid:24402349]
Rosales A, Sanbæk G, Jørgensen JJ. Stenting for chronic postthrombotic cava and iliofemoral occlusions. clinical outcome and midterm patency. Abstracts XXIII Annual Meeting European Society for Vascular Surgery (3 - 6 September 2009, Oslo, Norway): 59.
Maksimovi M, Maksimov M, Gojni M. Surgical treatment of ovarian cancer and early detection of venous thromboembolism. Eur J Gynaecol Oncol. 2011;32(4):415-418.
Bergan JJ. The Vein Book. Bergan JJ, editor. London-Oxford: Elsevier Academic Press; c2007. 617p
Ageno W. Rivaroxaban for the prevention of venous thromboembolism following major orthopedic surgery: the RECORD trials. Expert Rev Cardiovasc Ther. 2009;7(6):569-576. DOI: https://doi.org/10.1586/erc.09.37
Wik HS, Endern TR. Long-term quality of life after pregnancy-related deep vein thrombosis and the influence of socioeconomic factors and comorbidity. J Thromb Haemost. 2011;9(10):1931-1936. DOI: https://doi.org/10.1111/j.1538-7836.2011.04468.x
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.