Morphofunctional changes in the mucous membrane of the palate and cheek, gums and salivary glands in hypothyroidism

I. M. Ananevych, R. R. Barchuk, O. M. Repetska, O. H. Popadynets, O. V. Sahan, M. B. Pastukh, V. M. Pertsovych, N. M. Dubyna, O. D. Marchuk

Abstract


The paper represents the results of electronic microscopic study of morphofunctional state of the structural components of mucous membrane of the palate and cheek, greater salivary glands, gums during the 21st day of mercazolilum-induced hypothyroidism, which is modeled in 15 mature white outbred rats. In every studied organ there were found the same type of degenerative changes in the blood vessels, epithelium, and connective tissue framework. Thus, pathological changes are based on both vascular and connective tissue alterations that potentialize each other. Taking into account the pronounced reactivity of the studied structures, it is reasonable to study the dynamics of morphofunctional transformations phasing in order to find possible methods of prevention and timely correction. 


Keywords


mucous membrane of the palate and cheek; salivary glands; gums; hypothyroidism

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References


Gromakova IA. Age peculiarities of experimental hypothyroidism in rats. Fiziol.zhurn. 2002; 1: 80-86.

Oganian AV. Morphological changes in teeth-jaw system in experimental hypothyroidism and protective action of antioxidant “Mexidol”. Novoye v teorii i praktike stomatologii: Sb. nauch. Rabot StGMA. 2010: 101-102.

Skrypnyk NV. Role of iodine deficiency and hypothyroidism in the development of metabolic syndrome. Visnyk naukovykh doslidzhen. 2012; 3: 35-39.

Troshina EA, Platonova NM, Abdulkhabirova FM. [et al.] Structural and functional state of the thyroid gland in adolescents in the region with iodine deficiency. Pediatriya. Zhurnal im. G.N. Speranskogo. 2010; 89: 5: 19-24.

Turchina SI. Changes in thyroid status of adolescents with diffuse nontoxic goiter at the stages of puberty. Problemy endokrinnoy patologii. 2010; 4: 19-25.

Charnosh SM. Comparative characteristics of three experimental models of hypothyroidism. Visnyk naukovykh doslidzhen. 2007; 2: 113-115.




Copyright (c) 2017 I. M. Ananevych, R. R. Barchuk, O. M. Repetska, O. H. Popadynets, O. V. Sahan, M. B. Pastukh, V. M. Pertsovych, N. M. Dubyna, O. D. Marchuk

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