Variant Anatomy of the Posterior Lobe of the Human Cerebellum
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Keywords

human
cerebellum
anatomical variability

Abstract

The objective of study was to define the diversity of individual anatomical variability and common factors of variant anatomy of the cerebellum posterior lobe (vermis lobules VI–VII (Neocerebellum), lobule VIII (pyramis), lobule IX (uvula)).The study involved 230 cerebella of people of both sexes, who died of causes unrelated to brain pathology (20–99 years old). Midsagittal sections of the cerebellar vermis were investigated.Posterior lobe of the human cerebellum includes fifth, sixth and seventh branches of white matter. The fifth branch forms the basis of lobules VI–VII. The sixth branch forms the basis of lobule VIII (Pyramis), the seventh branch branches forms the basis of lobule IX (Uvula). The branching of white matter of these three lobules is Y–like: the main trunk of the white matter is divided into two main branches (upper and lower), which generate one or two secondary branches into the lobule. Depending on the characteristics of white matter branching, namely the number and location of the secondary branches, classification of the variants of the lobules of the posterior cerebellar lobe was described including 14 variants.Described shape variants of the cerebellar lobules can be used as criteria for modern diagnostic imaging techniques for the diagnosis of various diseases of the CNS. The data can be used as the basis for atlases of serial sections of the cerebellum.
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References

Anderson C.M., Rabi K. Cerebellar Lingula Size and Experiential Risk Factors Associated with High Levels of Alcohol and Drug Use in Young Adults Cerebellum. Neuroscience. 2010; 9 (2): 198–209.

Baillieux H, DeSmet H, Paquier P, DeDeyn P, Marien P. Cerebellar neurocognition: Insights from the bottom of the brain. Clinical Neurology and Neurosurgery. 2008; 110: 763–773.

Berquin P.C. Giedd J.N., Jacobsen L.K., Hamburger S.D., Krain A.L., Rapoport J.L. Cerebellum in attention–deficit hyperactivity disorder – A morphometric MRI study. Neurology. 1998; 50: 1087–1093.

DelBello M.P. MRI analysis of the cerebellum in bipolar disorder: a pilot study. Neuropsychopharmacology. 1999; 21: 63–68.

Larsell O., Jansen J. The comparative anatomy and histology of the cerebellum. III. The human cerebellum, cerebellar connections, and the cerebellar cortex. University of Minnesota Press. Minneapolis. 1972: 268

Leiner H., Leiner A., Dow R. Does the cerebellum contribute to mental skills? Behavioral Neuroscience.1986; 100: 443–454.

Leonard J. R., Ojemann. J. G. Dandy–Walker Syndrome. Youmans Neurological Surgery, Philadelphia. Elevier Inc. 2004; 3: 3285–3288.

Manni E., Petrosini L. A century of cerebellar somatotopy: A debated representation. Nature Reviews Neuroscience. 2004; 5: 241–249.

Schmahmann JD. An emerging concept: The cerebellar contribution to higher function. Archives of Neurology. 1991; 48: 1178–1187.

Schmahmann JD. From movement to thought: Anatomic substrates of the cerebellar contribution to cognitive processing. Human Brain Mapping. 1996; 4: 174–198.

Schmahmann, JD., editor. The cerebellum and cognition. International Review of Neurobiology. Vol. Academic Press. San Diego. 1997.

Stoodley C.J. Distinct regions of the cerebellum show gray matter decreases in autism, ADHD, and developmental dyslexia. Frontiers in Systems Neuroscience. 2014; 92 (8): Р.2–17.

Stoodley CJ, Schmahmann JD. Functional topography in the human cerebellum: A meta–analysis of neuroimaging studies. NeuroImage 2009; 44: 489–501.

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