Clinical evolution of Spitz nevi
PDF

Keywords

dermatoscopy
skin tumors
Spitz nevus
“Prediction without pigment” algorithm
“Chaos and Clues” algorithm

Abstract

Nevus Spitz is a benign melanocytic proliferation, first described in 1948 by Sophie Spitz as a childhood melanoma. Initially, it was described as an erythematous papule or node, but further studies of the Spitz nevus proved that in 71-92% cases it is a pigmented formation. This pigmentation is often quite intense due to the rapid growth of the formation, which leads to the need for differential diagnosis with skin melanoma. After all, dermatoscopy can be used for this purpose and, when applying this research method, typically a pattern of an exploding star formed by streaks of linear pigmentation and symmetrically located pigment globules placed in the peripheral zone can be revealed. In case of non-pigmented Spitz nevus, spot vessels and reticular depigmentation are visualized. Both pigmented and non-pigmented forms of Spitz nevus in the process of evolution can regress partially or completely. Several clinical cases of different types of spitzoids, both typical and atypical, based on the non-clinical, dermatoscopic and histological diversity of the Spitz nevi, have been demonstrated in the article. Their macroscopic and dermatoscopic features as well as probable signs of dynamic changes are indicated in order to facilitate their recognition by other specialists.

https://doi.org/10.21802/gmj.2020.2.13
PDF

References

Spitz S. Melanomas of childhood. The American Journal of Pathology 1948; 24: 591-609.

Lyon VB. The Spitz Nevus: Review and Update. Clinics in Plastic Surgery 2010; 37: 21-33. DOI: https://doi.org/10.1016/j.cps.2009.08.003 [PMid:19914455]

Argenziano G, Zalaudek I, Ferrara G, Hofmann-Wellenhof R, Soyer HP. Proposal of a new classification system for melanocytic naevi. British Journal of Dermatology 2007; 157: 217-227. DOI: https://doi.org/10.1111/j.1365-2133.2007.07972.x [PMid:17553053]

Pinheiro AMC, Amorin AG, Friedman H, Pereira GA, Varella TCN. Nevo de Spitz: Relato de caso e dermatoscopia. Anais Brasileiros de Dermatologia 2010; 85: 555-557. DOI: https://doi.org/10.1590/S0365-05962010000400021 [PMid:20944920]

Brancaccio G, Brunetti B, Fulgione E, Moscarella E, Alfano R, Argenziano G. Evolution of pigmented Spitz naevi with starburst pattern during childhood. Journal of the European Academy of Dermatology and Venereology 2019; 33: 29-30. DOI: https://doi.org/10.1111/jdv.15138

Moscarella E, Lallas A, Kyrgidis A, Ferrara G, Longo C, Scalvenzi M, et al. Clinical and dermoscopic features of atypical Spitz tumors: A multicenter, retrospective, case-control study. Journal of the American Academy of Dermatology 2015; 73: 777-784. DOI: https://doi.org/10.1016/j.jaad.2015.08.018 [PMid:26475536 PMCid:PMC4806681]

Rosendahl C, Cameron A, McColl I, Wilkinson D. Dermatoscopy in routine practice: Chaos and Clues. Australian Family Physician 2012; 41: 482-487.

Rosendahl C, Cameron A, Tschandl P, Bulinska A, Zalaudek I, Kittler H. Prediction without Pigment: a decision algorithm for non-pigmented skin malignancy. Dermatology Practical & Conceptual 2014; 4: 59. DOI: https://doi.org/10.5826/dpc.0401a09 [PMid:24520516 PMCid:PMC3919842]

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Downloads

Download data is not yet available.