Dynamics of Recovery of Functions of the Nasal Cavity in Patients with Aspirin-Intolerant Polypous Rhinosinusitis in the Postoperative Period

Ivanna Koshel

Abstract


Surgical interventions in the nasal cavity are accompanied by reactive phenomena in the postoperative period. On their background the process of physiological regeneration is disorganized resulting in impaired physiological functions of the nasal cavity.

The objective of the research was to study the recovery process of the main physiological functions of the nasal cavity in patients with aspirin-intolerant polypous rhinosinusitis in the postoperative period.

Materials and methods. 80 patients with aspirin-intolerant polypous rhinosinusitis at the age of 24-57 years were operated on.All the patients were divided into 2 groups: the control group included 30 patients; the main group comprised 50 patients.Patients of the control group received nasal cavity cleaning, nasal mucosa anemisation, irrigation therapy since the first day of the postoperative period.Patients of the main group received an herbal drug BNO-101 additionally. The effectiveness was assessed on the 3rd, 7th and 10th days of treatment.

Results. The postoperative rehabilitation with the inclusion of botanical preparation BNO-101 provided a significant improvement of nasal breathing, mucociliary transport rate and indicators of nasal peak flowmetry compared to the control group. Despite subjective improvement of nasal breathing the indicators of the peak expiratory flow rate in the main group were 34.2% lower than the norm while in the control group they were 54.7% lower than normal ones thereby justifying further treatment.

Conclusions. The postoperative rehabilitation of patients with aspirin-intolerant polypous rhinosinusitis provided more rapid improvement of the main functions of the nasal cavity compared to the control group.


Keywords


polypous rhinosinusitis; aspirin intolerance; postoperative rehabilitation

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References


Bezshapochnyy SB, Hasyuk VV, Loburets VV. Kliniko-morfologicheskie aspekty rinosinusitov. Bezshapochnyy SB. Kyiv: 2013. 150 p

Koshel IV, Dudii PF, Ryzhyk VM, et al. Aspіrynova trіada: novі pohliady na etіopatohenez і dіahnostyku. Ultrazvukova perynatalna diahnostyka. 2010;30:153–154

Lapach SN, Chubenko AV, Babich PN. Statisticheskie metody v mediko-biologicheskikh issledovaniyakh s ispolzovaniyem Exel. Kyiv: Morion; 2000. 320 p

Naumenko OM, Tereshchenko VP, Yushchenko VM. Metod protyretsydyvnoho likuvannia polipoznoho rynosynuiitu. ZhVNHKh. 2012;3:155–156

Popovych VI, Kovalchuk LYe, Ersteniuk HM, Ryzhyk VM, Koshel IV. Aspirynova triada, yak metabolichne zakhvoriuvannia. ZhVNHKh. 2009;2:76–86

Popovych VI. Khirurhichne vtruchannia ta peryoperatsiina terapiia pry aspirynovomu nazalnomu polipozi. Rynolohiia. 2012;2:48–57

Savchuk OI. Rannia pisliaoperatsiina reabilitatsiia khvorykh na khronichni rynosynuiity [extended abstract of dissertation for Doctor of Medical Science]. 2009. 36 p

Fokkens WJ, Lund VJ, Mullol J, Bachert C, Alobid I, Baroody F, et al. EPOS 2012: European position paper on rhinosinusitis and nasal polyps 2012. A summary for otorhinolaryngologists. Rhinology. 2012 Mar;50(1):1–12. [PMid: 22469599]

Melzer J, Saller R, Schapowal A, Brignoli R. Systematic Review of Clinical Data with BNO-101 (Sinupret?) in the Treatment of Sinusitis. Forschende Komplementärmedizin / Res Complement Med. 2006 Apr 19;13(2):78–87. DOI: http://doi.org/10.1159/000091969

Rimmer J, Fokkens W, Chong LY, Hopkins C. Surgical versus medical interventions for chronic rhinosinusitis with nasal polyps. In: Rimmer J, editor. Cochrane Database of Systematic Reviews. Chichester, UK: John Wiley & Sons, Ltd; 2014. DOI: http://doi.org/10.1002/14651858.CD006991.pub2

Rossi A, Dehm F, Kiesselbach C, Haunschild J, Sautebin L, Werz O. The novel Sinupret® dry extract exhibits anti-inflammatory effectiveness in vivo. Fitoterapia. 2012 Jun;83(4):715–20. DOI: http://doi.org/10.1016/j.fitote.2012.02.008

Sharma R, Lakhani R, Rimmer J, Hopkins C. Surgical interventions for chronic rhinosinusitis with nasal polyps. In: Sharma R, editor. Cochrane Database of Systematic Reviews. Chichester, UK: John Wiley & Sons, Ltd; 2014. DOI: http://doi.org/10.1002/14651858.CD006990.pub2

Yan Y, Gordon WM, Wang D-Y. Nasal epithelial repair and remodeling in physical injury, infection, and inflammatory diseases. Curr Opin Otolaryngol Head Neck Surg. 2013 Jun;21(3):263–70. DOI: http://doi.org/10.1097/MOO.0b013e32835f80a0

Yaremchuk S, Zabolotny D, Vareniuk І, Makarchuk N, Veselsky S. Sinupret® oral drops protect against respiratory epithelium atrophy in experimental acute rhinitis. Clin Phytoscience. 2015 Dec 6;1(1):8 DOI: http://doi.org/10.1097/MOO.0b013e32835f80a0




DOI: http://dx.doi.org/10.21802/acm.2016.2.1

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