Calcium Metabolism Indicators in Patients with Generalized Periodontitis and Hypertension

T I Vivcharenko, M M Rozhko

Abstract


The objective of the study is to determine the level of calcium in patients with hypertension of the II degree and generalized periodontitis of the II degree.

There were examined 30 patients with hypertension of the II degree with generalized periodontitis of the II degree. Patients’ age ranged from 35 to 54 years.  These patients were in the main group. Treatment of patients included taking the medicine “Ca-D3 NIKOMED”.

The control group included 10 patients without general somathic pathology and with healthy periodontitis of the same age.  The results obtained were subject to variational and statistical processing.

The analyses were carried out before and 3 months after the treatment. The level of general Ca in patients with generalized periodontitis of the II degree and hypertension of the II degree before the treatment was 1.66±0.03 mmol/l (p<0.001) (norm 2.15-2.5 mmol/l). In the patients of control group this figure was 2.33±0.04 mmol/l (p<0.001).

After 3 months the level of general Ca in patients with generalized periodontitis of the II degree and hypertension of the II degree was 1.87±0.03 mmol/l (p<0.001).

The level of ionized Ca in patients with generalized periodontitis of the II degree and hypertension of the II degree before the treatment was 0.36± 0.01 mmol/l (p<0.001); after the treatment the level of ionized Ca was 0.41±0.01 mmol/l (p<0.001). The level of ionized Ca in control group patients was 1.03±0.02 mmol/l (p<0.001).

We can conclude: according to the analysis of levels of general and ionized calcium in serum of patients with generalized periodontitis of the II degree and hypertension of the II degree we can conclude that these indexes are lower than normal; patients with generalized periodontitis of the II degree and hypertension of the II degree have increased levels of general calcium and ionized calcium in serum after taking the drug “Ca-D3 NIKOMED”during 3 months.


Keywords


hypertension; generalized periodontitis; Ca

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References


Biryukova EV. Osteoporosis: the view of endocrinologist. Farmateka. 2012; 1-12: 32-39.

Chang WT. Calcium, magnesium, and phosphate abnormalities in the emergency department. Emerg Med Clin North Am. 2014; 32(2): 349-366. DOI: https://doi.org/10.1016/j.emc.2013.12.006 [PMid:24766937]

Courbebaisse M, Souberbielle JC. Phosphocalcic metabolism: regulation and explorations. Nephrol Ther. 2011; 7(2): 118-138. DOI: https://doi.org/10.1016/j.nephro.2010.12.004 [PMid:21273150]

Dedukh NV, Poshelok DM, Malyshkina SV. Modeling and remodeling of bone (literature review). Ukrayinsky morfolohichny almanakh. 2014; 12(1): 107-111.

Demidov VI, Zhidomorov NYu, Gromov OA. The Role of Calcium, vitamin D3, and osteotropic minerals in the prevention and complex treatment of tibial fractures: results of a randomized placebo-controlled experiment. Lechashchiy vrach. 2014; 12: 42-46.

Ghosh A K. Disorders of calcium, phosphorus and magnesium metabolism. J Assoc Physicians India. 2008; 56: 613-621. [PMid:19051708]

Gusak EV. The microelement composition of long and mixed bone of the skeleton is normal. Ukrayinsky morfolohichny almanakh. 2010; 8(4): 51-55.

Kamilov FH, Farshatova ER, Enikeev DA. Cellular-molecular mechanisms of bone tissue remodeling and its regulation. Fundamentalnye issledovaniya. 2014; 7: 836-842.

Kutia SA. Age peculiarities of calcium-phosphorus metabolism status in rats exposed to gravity overload. Ukrayinsky morfolohichny almanakh. 2009; 4: 80-82.

Masalova NN, Zakharenko RV. The state of phosphoric-calcium and bone metabolism in normal and in thyroid gland function abnormalities. Dalnevostochny meditsynskiy zhurnal.2009; 2: 122-125.

Netiukhaylo LH, Filatova VL, Filatova OV. Water-salt exchange (literature review). Visnyk problem biolohiyi i medytsyny. 2012; 1(91): 32-37.

Peacock M. Calcium metabolism in health and disease. Clin. J Am Soc Nephrol. 2010; 5(1): 23-30. DOI: https://doi.org/10.2215/CJN.05910809 [PMid:20089499]

Povorozniuk VV, Grigorieva NV. Nutrition and bone tissue. Problemy stareniya i dolgoletiya. 2011; 20(2): 148-158.

Rozhynskaya L. Ya. Diagnosis and treatment of osteoporosis. Klinicheskaya herontologiya. 2007; 2: 37-46.

Sharon MM. Disorders involving calcium, phosphorus, and magnesium. Prim Care. 2008; 35(2): 215-233. DOI: https://doi.org/10.1016/j.pop.2008.01.007 [PMid:18486714 PMCid:PMC2486454]

Shevchuk VH, Moroz VM, Belan SM et al. Physiology: textbook for students of higher medical schools. Nova knyha. 2012; 448.

Wieliczko M, Matuszkiewicz-Rowińska J. Calcium homeostasis. Wiad Lek. 2013; 66(4): 299-302. [PMid:24490481]

Yakymyuk DI, Krivetsky VV, Banul BYu et al. Modern ideas about the growth, development and formation of human bone skeleton. Bukovynsky medychny visnyk. 2013; 17(2): 181-185.




DOI: http://dx.doi.org/10.21802/acm.2018.1.1

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