Effect of Urogenital Infections on the Development of Placentary Dysfunction in Women Belonging to Risk Groups

A Hoshovska, I Byrchak, V Hoshovskyi


The study involved 36 pregnant women with inflammatory diseases of female genital organs and 40 placentas of women with the physiological course of pregnancy and childbirth. Immunohistochemical and histological methods were used.  It has been established that pregnant women with urogenital infections compared to those with physiological pregnancy had a lower concentration of the placental lactogen hormone and more active proapoptic protein of the BAX against the background of the unchanged concentration of the anti-apoptotic protein Bcl-2 in the cytoplasm of the invasive cytotrophoblast of the basal lamina.


inflammatory diseases of female genital organs; placenta; invasive cytotrophoblast

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DOI: http://dx.doi.org/10.21802/acm.2017.2.3


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