Population-Based Estimation of the Prevalence of Dysplastic Dependent Pathology of Bronchopulmonary System among Children and the Risk of its Development Considering the Complex of Antenatal and Genealogical Factors

A. F. Shypko

Abstract


Based on the study of the prevalence of potential genealogical and antenatal factors the most informative ones were determined. Their prognostic value was used as a criterion for assessing the risk of developing dysplastic dependent pathology of the bronchopulmonary system in children. Standardized pathometric tabular algorithm was developed using the Wald’s sequential analysis modified by Hubler EV. An example of its application at the individual level was presented. The given algorithm was verified among children of both groups using the inverse method. The type I error rate (there was a high risk in the absence of pathology) was α=12.0%, and the type II error rate (there was a low risk in the presence of pathology) was β=9.8%. The specificity of the algorithm was 91.2% and its sensitivity was 88.0% that allows us to recommend it for using in the system of medical and social monitoring.

Keywords


social medicine; children’s health; risk factors; bronchopulmonary system; prediction

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References


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