Hemochromatosis and Hemosiderosis in Children

  • Z. V. Vovk Department of Children Diseases of Postgraduate Medical Education Faculty Ivano-Frankivsk National Medical University, Ivano-Frankivsk
  • O. L. Tsymbalista Department of Children Diseases of Postgraduate Medical Education Faculty Ivano-Frankivsk National Medical University, Ivano-Frankivsk
  • O. B. Sinoverska Department of Children Diseases of Postgraduate Medical Education Faculty Ivano-Frankivsk National Medical University, Ivano-Frankivsk
Keywords: hemochromatosis, hemosiderosis, iron, chelation therapy, newborn

Abstract

Hemochromatosis involves the group of diseases of different etiology and morphological features of affected organs. Hemochromatosis is usually inherited; however, it can also develop secondary to various diseases. In this case, the accumulation of iron in parenchymal organs in the form of hemosiderin leading to disruption of their structure and function is typical. An early or preclinical diagnosis of the disease is of great importance for its prognosis as in case of untimely diagnosis significant abnormalities in various organs and systems are observed. 

References

Alekseev NA. Аnaemia. SPB. Hippokrat. 2004;512.

Mamaeva NN, Radova SI. Haematology: guidance for doctors. Mamaeva NN, Radova SI, editors. Spb. Spets. Lit. 2008;543.

Zakharova IN, Malova NE, Ruchnina EV. The role of iron in human organism. Ros. pediatrich. zhurn. 2007;1:31-34.

Romanova AF. Clinical haematology. Romanova AF, editor. Meditsina. Kiev. 2006;456.

Kazyukova TV, Levina AA, Tsvetaeva NV, et al. Regulation of iron metabolism. Pediatriya. 2006;6:94-101.

Vilms EA, Turchaninov LV, Turchaninova MS. Microelementosis in child population in the metropolis: epidemiological characteristics and possibilities of prevention. Pediatriya. Zhurnal im. H.N. Speranskogo. 2011;1(90):96-101.

Marushko YuV. Trace elements and state of immunity in children. Aktualna infektol. 2013;1.

Published
2015-12-31
Section
Original Research